Startups
Cleveland Clinic Innovations
Cleveland, Ohio, United States
Cleveland Clinic Innovations is the technology-commercialization arm of Cleveland Clinic, a nonprofit academic medical center operated by The Cleveland Clinic Foundation. Formed in2000, it advances caregiver inventions through assessment, technology development, intellectual-property protection, licensing, startup creation, strategic partnerships and venture investing. Its Cleveland Clinic Ventures team creates and invests in spinout companies and supports formation, management, governance, financing and strategic transactions. This profile represents the institutional commercialization and Ventures unit; public sources do not establish a separate independently capitalized venture fund manager. Its portfolio spans medical devices, diagnostics, therapeutics, digital health and artificial intelligence. Relevant examples include Enspire DBS Therapy’s stroke-rehabilitation neuromodulation, NeuroTherapia’s neuroinflammation therapies, AxoNeural’s spinal-cord-injury therapeutics, Infuseon’s brain drug-delivery catheter, Floreo’s virtual-reality developmental therapy, Bayesian Health’s predictive clinical AI and Dyania Health’s clinical-data AI. The current directory names20 leadership, business-development/licensing and Ventures staff. Chief D. Geoffrey Vince and Ventures Executive Director JD Friedland lead the commercialization and investing work. The Global Venture Philanthropy Fund is a donor-supported innovation program mentioned in Clinic publications; its size and close are not publicly disclosed in the reviewed sources, and it is not assumed to be a conventional closed LP venture fund. Healthcare-system assets, innovation outcomes, research budgets, licensing partnerships and venture capital committed to portfolio companies are not treated as manager fund-close cash. This unit is distinct from unrelated Cleveland Avenue and Cleveland Capital Management. Ohio’s2023 economic-development annualreport also names CCF Ohio BioValidation Funds I–VI as Foundation pre-seed investment capitalization vehicles, reporting state funds awarded, expenditures and cost share. Those figures and project-end dates are not treated as total LP commitments or fund-close dates. These government-backed capitalization vehicles and the philanthropic program are distinct from conventional closed LP venture funds.
Founded 2000
Team
Bill KolosiDirector, Medical Devices |
 D. Geoffrey VinceChief |
Daniel LeeSenior Director, Digital Health & Therapeutics |
Giedre RuzgaiteAssociate Director, Digital Health & Therapeutics |
Jeremy LangsamAssociate |
Jerry WilminkDirector, Digital Health |
Joe BaroneDirector, Therapeutics & Diagnostics |
 Jon David FriedlandExecutive Director, Ventures |
 Joseph RichExecutive Director |
 Linda Li, CFAPartner |
Linnea GottlanderManager, Innovations Governance & Contract Compliance |
Michael AustriacoGeneral Manager, Assessment |
Partha PaulDirector, Medical Devices |
Robin CrottyDepartment Administrator |
 Saqib SachaniDirector, Therapeutics & Diagnostics |
Sarah StampGeneral Manager, Engagement |
Shawn ZimmerSenior Director, Finance |
Sonja O’MalleyGeneral Manager, Business Development & Licensing |
 Todd SchwarzingerPartner |
Zach EisenSenior Principal |
Investments
| $10M2026-01-13 |  Enspire DBS Therapy | Genesys Capital, Cleveland Clinic Innovations, JobsOhio Ventures |
| $—2023-08-01 | Enspire DBS Therapy | Cleveland Clinic Innovations, JobsOhio Ventures |
| $—Unknown date |  AxoNeural Therapeutics | Cleveland Clinic Innovations |
| $—Unknown date |  Floreo | Cleveland Clinic Innovations |
| $—Unknown date | Bayesian Health | Cleveland Clinic Innovations |
| $—Unknown date | Ayble Health | Cleveland Clinic Innovations |