Firms

Polaris Innovation Fund

Polaris Innovation Fund

Boston, Massachusetts, United States

polarispartners.com

Polaris Innovation Fund is the specialist early-stage biomedical company-building programme advised by LS Polaris Innovation Fund Management, L.L.C., separate from the main Polaris Partners and Growth fund advisers. The retained historical LS Polaris investment identity represents this specialist adviser and its fund mandate. Current April8,2026 legal disclosures name two specialized affiliate vehicles: LS Polaris Innovation Fund, L.P. and Polaris Innovation Fund II, L.P. The original LS fund was formed in2017; an April2,2019 SEC exempt-reporting-adviser final filing identifies historical CRD290691, rather than establishing current standalone SEC registration. Current own legal disclosures independently confirm the adviser identity. The programme supports early academic research and active company creation across therapeutic platforms, diagnostics, life-science tools and healthcare technologies. Its current published eight-member directory includes six investment professionals and two scientific advisory committee members; outside MIT appointments are advisory affiliations, not presumed fund employment. Relevant published specialist portfolio includes ALS therapeutics company QurAlis, neurology-focused Muna, gut-brain-axis Kallyope, Alzheimer and other neurological diagnostic developer SunBird Bio, teen mental-health BeMe, Oui and Sesh, AI/CRISPR drug-discovery Engine Biosciences and conversational AI medication-management UpDoc. Portfolio listings include historical/exited companies and do not establish current operating status, actual cash allocation or financing stage. The two real specialist fund vehicles are recorded with undisclosed capital and close date; no gross assets, insurance LP carrying value, target or main Polaris fund close is treated as cash raised by these vehicles. Existing two legacy institutional checks remain preserved; the main platform Investor3220 remains separate and is not given a duplicate specialist allocation.

Founded
2017
Type
Venture capital

Funds2

  • LS Polaris Innovation Fund, L.P.—

    Exact specialized legal affiliate fund managed by LS Polaris Innovation Fund Management LLC, according to current April8,2026 own legal disclosures. Capital amount and actual final close date unverified; NULL values intentional. Gross assets, target, LP carrying values and commitments excluded from closed capital.

  • Polaris Innovation Fund II, L.P.—

    Exact specialized legal affiliate fund managed by LS Polaris Innovation Fund Management LLC, according to current April8,2026 own legal disclosures. Capital amount and actual final close date unverified; NULL values intentional. Gross assets, target, LP carrying values and commitments excluded from closed capital.

Team

Operations and support

Alexandra CantleyAlexandra CantleyManaging Partner
Amy SchulmanAmy SchulmanManaging Partner
Daniel AndersonDaniel AndersonScientific Advisory Committee Member
Eileen McGuireEileen McGuireManaging Partner
Manik KuchrooManik KuchrooSenior Associate
Nil GuralNil GuralPrincipal
Robert LangerRobert LangerScientific Advisory Committee Member
Terry McGuireTerry McGuireFounding Partner

Co-investing

Amgen Ventures
Catalio Capital Management
Dementia Discovery Fund
Dolby Family Ventures
Droia Ventures

Investments

$88M2023-03-09QurAlisDroia Ventures, EQT Life Sciences, Sanofi Ventures, INKEF Capital, Dementia Discovery Fund, Mission BioCapital, Polaris Innovation Fund, Amgen Ventures, ALS Investment Fund, Sanford Biosciences LLC, MP Healthcare Venture Management, Dolby Family Ventures, Mission Bay Capital, Mitsui & Co. Global Investment, Inc.
$—2021-10-07Neumora Therapeutics, Inc.ARCH Venture Partners, Catalio Capital Management, F-Prime Capital, Alexandria Venture Investments, Polaris Innovation Fund, re.Mind Capital
$42M2020-05-13QurAlisINKEF Capital, Dementia Discovery Fund, Mission BioCapital, Droia Ventures, Polaris Innovation Fund, Amgen Ventures, Sanford Biosciences LLC, MP Healthcare Venture Management, Dolby Family Ventures, Mitsui & Co. Global Investment, Inc.
$110MUnknown dateSatellite BioLightspeed, Catalio Capital Management, Polaris Partners, Polaris Innovation Fund