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Wave Life Sciences

Cambridge, Massachusetts, United States

Cambridge, Massachusetts biotechnology company developing investigational RNA medicines using its PRISM platform, which combines stereochemistry, human genetics and modalities including RNA editing, RNA interference, antisense silencing and splicing. Its neuroscience work includes Huntington’s disease, alongside programs in Duchenne muscular dystrophy, alpha-1 antitrypsin deficiency, obesity and liver disease. Wave was incorporated in Singapore in 2012, listed on Nasdaq as WVE in 2015, and completed redomiciliation to Delaware after trading on 7 August 2026, with its new common stock beginning Nasdaq trading on 10 August. Paul Bolno leads the company; its published leadership directory contains 11 executives and nine board members, with Bolno in both groups. GSK is an equity investor and research collaborator. As of 7 October 2026, the RNA medicines discussed here remain investigational: FDA feedback on the planned WVE-006 registrational pathway is distinct from approval or trial initiation. Equity fundraising is tracked separately from commercial research, licensing and milestone payments.

Founded 2012

Team

Aik Na TanDirector
Chandra VargeeseChandra VargeeseChief Technology Officer
Chris FrancisChris FrancisChief Strategy Officer
Chris WrightChris WrightChief Medical Officer
Christian HenryChristian HenryChair of the Board
Daryn LewisDaryn LewisSenior Vice President, Head of Human Resources
Erik IngelssonErik IngelssonChief Scientific Officer
Ginnie (Hsiu-Chiung) YangGinnie (Hsiu-Chiung) YangSenior Vice President, Translational Medicine
Gregory VerdineFounder and Director
Heidi WagnerDirector
Kyle MoranKyle MoranChief Financial Officer
Linda RockettLinda RockettSenior Vice President, General Counsel
Monika VnukMonika VnukChief Business Officer
Paul BolnoPaul BolnoPresident and Chief Executive Officer · Director
Sridhar VaddeboinaSridhar VaddeboinaSenior Vice President, Chemistry, Manufacturing, and Controls

Investments

$402M2025-12-110 participations
$230M2024-09-270 participations
$115M2023-12-110 participations
$50M2023-01-26GSK
$70M2022-06-160 participations
$100M2017-04-180 participations
$30M2016-05-05Pfizer
$111M2015-11-160 participations
$66M2015-08-18Foresite Capital, RA Capital Management, Fidelity Management & Research Company, New Leaf Venture Partners, Redmile Group, Jennison Associates, Cormorant Asset Management
$18M2015-02-02RA Capital Management