Startups
TRIMTECH Therapeutics
Cambridge, United Kingdom
TRIMTECH Therapeutics Limited is a Cambridge, UK biotechnology company developing small-molecule targeted protein degraders for neurodegenerative and inflammatory disorders, including Alzheimer’s, Parkinson’s and Huntington’s disease. Incorporated on November21,2023 under company15299951, it is registered at Babraham Research Campus and arose from research by Leo James at the MRC Laboratory of Molecular Biology and William McEwan at the UK Dementia Research Institute, with Cambridge Innovation Capital, the Dementia Discovery Fund and entrepreneur-in-residence Damian Crowther. Its TRIMTAC and TRIMGLUE platforms seek to recruit the TRIM21 ubiquitin ligase to remove disease-associated protein aggregates while preserving functional proteins. These are drug-discovery programmes; the published research and financing materials do not establish approved medicines or human efficacy. CEO Nicola (Nicki) Thompson leads a team with targeted-protein-degradation, neuroscience, chemistry and biotechnology-development experience. The company publishes management, board and scientific advisers separately; adviser roles are not automatically employment or personal investment. Its own March5,2025 release confirms a closed USD31million seed financing, followed by an actual USD14million seed extension announced June23,2026. The June release reports USD47million cumulative seed funding, although31plus14equals45; no unexplained USD2million transaction is inferred. The about page also contains a conflicting currency notation for the extension, so the dated financing release supplies the retained USD amount. Existing personal investment-history attributions remain distinct from source-proven institutional buyers.
Founded 2023
Team
 Alessio CiulliChair of SAB |
 Alex AlanineSVP Head of Chemistry |
 Alison LawtonIndependent Chair |
 Andrea TestaVP, Chemistry |
 Damian CrowtherCo-founder, Head of Research |
 Dean CliftSenior Director, Biology |
 Hakan GokerNon-Executive Director |
 Julia JonesFractional CFO |
 Laurence BarkerNon-Executive Director |
 Leo JamesChief Scientific Adviser; Member of SAB and TRIMTECH Co-founder |
 Lucy Edwardes JonesNon-Executive Director |
 Marie-Claire PeakmanNon-Executive Director |
 Michael AnsteyNon-Executive Director |
 Michael HuttonMember of SAB |
 Nadiya IshnazarovaNon-Executive Director |
 Will McEwanChief Scientific Adviser; Member of SAB and TRIMTECH Co-founder |
