503 Partners, formerly 3x5 Partners, is a Portland venture investment adviser focused on healthcare and resource-driven technologies such as water, energy, agriculture and sustainable materials. Its investment team joined American Century Investments in 2023 to build that manager’s private investment unit, while 503 Partners continues to report legacy investment vehicles and legal managers in its regulatory filings. Historical investments under the 3x5 name include Bonum Therapeutics, Good Therapeutics and Fervo Energy. Its retained 3x5 logo represents the historical brand.