Bonum Therapeutics develops dual-binding antibody medicines whose therapeutic activity switches on when a sensor binds a specified target and switches off when the molecule disengages. It uses this reversible regulation to concentrate cytokine activity in tumors and reduce effects elsewhere in the body. Its initial programs target cancer, with potential applications in autoimmune disease, metabolic disorders and pain. Bonum continued the team and retained platform of Good Therapeutics after Roche acquired that predecessor’s PD-1-regulated IL-2 program in 2022; the companies and financings are distinct.