Firms

Syncona

Syncona

Victoria House, Bloomsbury Square, London WC1B 4DA, United Kingdom · Syncona Limited registered office: Frances House, PO Box 273, Sir William Place, St Peter Port, Guernsey GY1 3RD

synconaltd.com

Syncona is a UK-based life science investment and company-building group founded by Wellcome in 2012. This profile represents the Syncona investment brand, distinguishing its Guernsey listed investment company Syncona Limited (registration 55514, formerly BACIT Limited, LSE: SYNC) from subsidiary Syncona Investment Management Limited (English company 10497864), its regulated alternative investment fund manager. The listed vehicle began business and trading on 26 October 2012; its 2016 transition acquired the original Syncona portfolio and adopted the Syncona name. Syncona funds and helps build biotechnology businesses, including gene and cell therapies, small-molecule drug discovery, neurological disease programmes and computational oncology. Current portfolio examples include Spur’s Parkinson’s disease gene therapy work, Beacon’s retinal gene therapies, Mosaic’s computational drug combinations and OMass’s molecular discovery platform. The September 2026 leadership changes made Chris Hollowood CEO and CIO, Samantha Roberts managing director, and Roel Bulthuis an executive partner. The separate listed-company board is chaired by Melanie Gee. Investments are held through corporate Syncona Holdings Limited; the capital pool is held in Syncona Investments LP Incorporated, whose sole limited partner is Syncona Limited. Permanent listed equity, sole-LP capital-pool assets and company investment commitments are distinguished from external multi-investor LP fund closes. Wellcome’s historical investment does not make it the buyer of every Syncona portfolio company.

Founded
2012
Type
Venture capital

Funds1

  • Syncona Investments LP Incorporated—

    Guernsey capital-pool partnership of the Syncona listed group. Syncona Limited is its sole limited partner and wholly owned Syncona GP Limited is general partner. This is a legal internal capital-pool vehicle, not an external multi-LP fund close. NAV, cash balances and annual capital deployed are not recorded as fund size. The portfolio holding company Syncona Holdings Limited is a separate corporate subsidiary.

Team

Operations and support

Alessio D'addabboAlessio D'addabboAnalyst (Syncona Investment Management Limited)
Anastasia PrechistenskayaAnastasia PrechistenskayaPeople Partner (Syncona Investment Management Limited)
Annabel ClarkAnnabel ClarkHead of Corporate Affairs (Syncona Investment Management Limited)
Caroline HorsfordCaroline HorsfordExecutive Assistant (Syncona Investment Management Limited)
Chris HollowoodChris HollowoodChief Executive Officer and Chief Investment Officer (Syncona Investment Management Limited)
Christina SeedChristina SeedGroup Reporting and Treasury Manager (Syncona Investment Management Limited)
Cindy WooCindy WooGovernance and Compliance Assistant (Syncona Investment Management Limited)
Edward HodgkinEdward HodgkinManaging Partner (Syncona Investment Management Limited)
Elisa PetrisElisa PetrisManaging Partner (Syncona Investment Management Limited)
Fiona FernandezFiona FernandezHead of Operations (Syncona Investment Management Limited)
Gemma MountfordGemma MountfordExecutive Assistant (Syncona Investment Management Limited)
Gian Piero ReverberiGian Piero ReverberiNon-Executive Director (Syncona Limited listed-company board)
Gonzalo GarciaGonzalo GarciaPartner (Syncona Investment Management Limited)
Gwenaelle PembertonGwenaelle PembertonExecutive Partner (Syncona Investment Management Limited)
Harriet Gower IsaacHarriet Gower IsaacChief People Officer (Syncona Investment Management Limited)
Helen D'SilvaHelen D'SilvaExecutive Assistant (Syncona Investment Management Limited)
Hitesh ThakrarHitesh ThakrarExecutive Partner (Syncona Investment Management Limited)
John RocheJohn RocheNon-Executive Director (Syncona Limited listed-company board)
Julie CherringtonJulie CherringtonNon-Executive Director (Syncona Limited listed-company board)
Kate ButlerKate ButlerChief Financial Officer (Syncona Investment Management Limited)
Kemal MalikKemal MalikSenior Independent Director (Syncona Limited listed-company board)
Kenneth GalbraithKenneth GalbraithChair of SIML and Executive Partner (Syncona Investment Management Limited)
Marc PerkinsMarc PerkinsGeneral Counsel (Syncona Investment Management Limited)
Melanie GeeMelanie GeeChair (Syncona Limited listed-company board)
Melina HoffmannMelina HoffmannAssociate (Syncona Investment Management Limited)
Nathaniel DahanNathaniel DahanPrincipal (Syncona Investment Management Limited)
Nikki PaddenNikki PaddenCorporate Partner (Syncona Investment Management Limited)
Nisha SethiNisha SethiLegal Counsel (Syncona Investment Management Limited)
Norman CrightonNorman CrightonNon-Executive Director (Syncona Limited listed-company board)
Paul SekhriPaul SekhriExecutive Partner (Syncona Investment Management Limited)
Pierre JoffrinPierre JoffrinSenior Associate (Syncona Investment Management Limited)
Raghd RostomRaghd RostomPrincipal (Syncona Investment Management Limited)
Richard WoosterRichard WoosterExecutive Partner (Syncona Investment Management Limited)
Roel BulthuisRoel BulthuisExecutive Partner (Syncona Investment Management Limited)
Samantha RobertsSamantha RobertsManaging Director (Syncona Investment Management Limited)
Sarah CrabtreeSarah CrabtreeHead of Legal (Transactions) (Syncona Investment Management Limited)
Sarah QianSarah QianAssociate (Syncona Investment Management Limited)
Stephen MolumbyStephen MolumbyHead of Portfolio Management and FP&A (Syncona Investment Management Limited)
William DutsonWilliam DutsonGroup Accountant (Syncona Investment Management Limited)

Co-investing

Investments