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Circular Genomics

San Diego, California, United States

Circular Genomics develops blood-based circular RNA biomarkers and analytical tools for research into neurological and psychiatric disorders. Its CircPath platform profiles brain-derived circRNAs to investigate disease pathways, identify biomarkers and characterize patient cohorts. Published applications include Discover 1600+ for broad circRNA profiling, AD Detect for research into biomarker-defined Alzheimer’s disease biology, and AD Predict for research into future cognitive impairment and symptom progression. The current CircPath applications are labelled for research use only and are not intended for diagnostic procedures. The company also announced the historical launch of MindLight in September 2024, a blood assay intended to help clinicians assess antidepressant response in major depressive disorder; its present availability is unverified. Circular Genomics works with academic and biopharma partners on biomarker validation and licensed intellectual property, with headquarters at Lilly Gateway Labs in San Diego.

Founded 2021

Team

Alexander HafezCofounder; President and Board Director (historical 2021; current operating appointment unverified)
Andrew LechleiterCommercial Advisory Board Member
Carlos CruchagaScientific Advisory Board Member
Dave BlivinMember of the Board of Directors
Dave KarlanderChief Commercial Officer (appointed February 2024; current appointment unverified)
Eleni TzavaraScientific Advisory Board Member
Greg DeckerChief Financial Officer
Henrik ZetterbergHenrik ZetterbergScientific Advisory Board Member
James GranaCommercial Advisory Board Member
Joe Cook IIIMember of the Board of Directors
Kosmas KaradimitriouCofounder and Advising CIO (published November 2024; current advisory appointment unverified)
Laura ViachesCommercial Advisory Board Member
Madhukar H. TrivediMadhukar H. TrivediScientific Advisory Board Member
Melissa ReillyCommercial Advisory Board Member
Michael F. AckermannScientific Advisory Board Member
Michael WeinerMichael WeinerScientific Advisory Board Member
Nikolaos MelliosCofounder, Chief Scientific Officer and Member of the Board of Directors
Paul SargeantPresident and Chief Executive Officer, Member of Board of Directors
Phyllis Barkman FerrellPhyllis Barkman FerrellScientific Advisory Board Member
Ron RoccaMember of the Board of Directors
Roy PerlisScientific Advisory Board Member
Sami ShihabiChief Commercial Officer
Timothy HohmanScientific Advisory Board Member
Vishi SrinivasanSenior Director of Clinical Research (appointed February 2024; current appointment unverified)
Waneta TuttleMember of the Board of Directors

Investments