Firms

Yosemite

Yosemite

San Francisco, California, United States

yosemite.colinkedin.com

Yosemite is the San Francisco oncology-focused venture investment and research-philanthropy platform launched as an independent firm on August1,2023 after spinning out of Emerson Collective Health. Its regulated legal adviser is Yosemite Management, LLC, CRD326764 / SEC801-128248, headquartered at901BatteryStreet, SanFrancisco. The predecessor health strategy began at Emerson in2015; that history is distinct from the standalone2023 launch and manager ownership recorded from2022. Unrelated Japanese Yosemite, Yosemite Capital Management, Yosemite Conservancy and CRED’s Yosemite product are excluded. The firm finances therapeutics, diagnostics, tools, digital health and healthcare delivery, with a cancer non-lethal mission and verified AI drug-discovery/healthcare-software investments. It combines venture investing and incubation with a parallel donor-advised charitable grant programme. Its own February2026 release reports morethanUSD18M cumulatively deployed in research grants since2023; that is not a new debt round, paid LP corpus or a second corporate raise. The2023 launch states that Yosemite manages Emerson Health’s legacy ECI Health Funds as adviser; this does not retroactively change those historical subscribing buyers. Three March2026 SEC-reported private vehicles are separately recorded: Yosemite Fund I LP, Yosemite Fund II LP and Firefall Fund I LP. Primary counsel confirms USD200M first closing for FundI, while the issuer describes an oversubscribed200M+ firstclose; no unproved263M final corpus is inferred from its262.908M grossassetvalue. Own FundII announcement confirms morethan200M initialclose, whose exact corpus remains unpublished;350M is a target. Its January2026 FormD zero sold is a filing-date snapshot before later commencement, and March2026 ADV259.469M GAV is not closed LP commitments. Firefall is an affiliated private vehicle with unpublished corpus. The live firm website does not publish a complete staff or portfolio directory. This profile includes sixteen publicly named operating/legal affiliates and source-qualified historical/advisory roles; private headcount and unverified current ranks are not invented. AnnaDarbyshire’s former foundingCOO role and own transition to adviser are separated. Six genuine named portraits remain unavailable from accessible primary sources. Historical portfolio records and personal checks are preserved, including sparse ChaiDiscovery and duplicate Sage/SageCare representations queued for full issuer audits. Fourier Health’s actual8.4M seed announcedOctober17,2025 explicitly names Yosemite as lead; its individual check and subscribing fund are unpublished.

Founded
2023
Type
Venture capital

Funds3

  • Firefall Fund I, LP—

    Delawareprivatevehicle SEC805-7167940030, GPYosemiteGP I LLC. March2026 ADV reportsGAV1,046,626/fivebeneficialowners; corpus/closingdayNULL. Primary2025LomondSchedule13G identifies Firefall as nominee throughYosemiteFundI; 2.5Mshares held inaggregate do not revealpaidcash, pricedroundornewfundclose.

  • Yosemite Fund I, LP$200M

    Delaware venture vehicle, SECprivatefund805-5525518188, GPYosemiteGP I LLC. Primarylegalcounsel August1,2023 confirms200M firstclose; issuer says200M+oversubscribed. Structuredamount is the documentedfirstclosing tranche, not claimedexactfinalcorpus or additionalraise. Exactclosingday unpublished. March2026 GAV262,908,042 and53beneficialowners are asset/ownershipdisclosures, not newLPcash.

  • Yosemite Fund II, LP—

    Delawareventurevehicle formed2025, SEC805-1341551401, GPYosemiteGP II LLC. Ownprimary announcement confirms initialclose MORETHANUSD200M; structuredamountNULL becauseexactcorpusunpublished. USD350M Jan2026offering is target; FormD0sold is thatfiling snapshot. March2026ADVstatesoperationscommenced2026 andGAV259,469,000, notactualclosedLPcorpus. ExactclosingdayNULL.

Team

Operations and support

Abel NegussieAbel NegussieInvestment Team — Analyst title confirmed2023; current rank unpublished
Alexander SinghAlexander SinghInvestor — Healthcare and AI
Anna DarbyshireAnna DarbyshireFounding Chief Operating Officer — former · Adviser — own published transition
Beverly LuBeverly LuInvestor
Carrie Amy KiblerCarrie Amy KiblerGeneral Counsel and Chief Compliance Officer
Daniel McHughDaniel McHughLead Investor — Head of Investment Team
David Edward WilliamsChief Financial Officer
Emily KianTeam Member — specific current title unpublished
John AinslieJohn AinslieLife Sciences Investment Team — Analyst title confirmed2025
Kaleb NegussieTeam Member — specific current rank unpublished
Kunal Shah (Yosemite)Healthcare Investment Team — specific rank unpublished
Lauren Cantor WrightLauren Cantor WrightPrincipal
Matt BettonvilleMatt BettonvilleInvestor — Digital Health and Healthcare Delivery
Reed JobsReed JobsFounder and Managing Partner
Renee JayTeam Member — specific current title unpublished
Teya PeharExecutive Assistant — own profile professional description

Co-investing

General Catalyst
Liquid 2 Ventures
Metrodora Ventures
AIX Ventures
Alexandria Venture Investments

Investments