Entities

TRIMTECH Therapeutics Limited is a Cambridge, UK biotechnology company developing small-molecule targeted protein degraders for neurodegenerative and inflammatory disorders, including Alzheimer’s, Parkinson’s and Huntington’s disease. Incorporated on November21,2023 under company15299951, it is registered at Babraham Research Campus and arose from research by Leo James at the MRC Laboratory of Molecular Biology and William McEwan at the UK Dementia Research Institute, with Cambridge Innovation Capital, the Dementia Discovery Fund and entrepreneur-in-residence Damian Crowther. Its TRIMTAC and TRIMGLUE platforms seek to recruit the TRIM21 ubiquitin ligase to remove disease-associated protein aggregates while preserving functional proteins. These are drug-discovery programmes; the published research and financing materials do not establish approved medicines or human efficacy. CEO Nicola (Nicki) Thompson leads a team with targeted-protein-degradation, neuroscience, chemistry and biotechnology-development experience. The company publishes management, board and scientific advisers separately; adviser roles are not automatically employment or personal investment. Its own March5,2025 release confirms a closed USD31million seed financing, followed by an actual USD14million seed extension announced June23,2026. The June release reports USD47million cumulative seed funding, although31plus14equals45; no unexplained USD2million transaction is inferred. The about page also contains a conflicting currency notation for the extension, so the dated financing release supplies the retained USD amount. Existing personal investment-history attributions remain distinct from source-proven institutional buyers.

Aispire develops a real-time analytics and AI platform for broadband networks and industrial operations. Its operating layer combines network telemetry with subscriber experience to identify whether service problems originate in an operator’s network, an upstream content provider, or a customer’s home. It supports network troubleshooting, peering analysis, capacity planning, and an AI assistant for interpreting operational data. The platform also provides edge analytics and predictive maintenance for semiconductor and other manufacturing environments, plus embedded and white-label analytics. Aispire combines the technologies of Adapdix and Edge Intelligence, with the merged business adopting the Aispire brand in 2024.

Designs silicon-photonics chips that integrate lasers, modulators and other optical components for high-speed data communications and AI computing infrastructure.

Onyx Security builds a secure AI control plane for enterprises deploying autonomous agents and models. Its platform discovers AI assets across SaaS, cloud, endpoints and code, monitors agent reasoning and actions, and enforces security and governance policies at runtime. Supervisory agents and proprietary models can block unsafe actions, require human approval, narrow an agent’s permissions or redirect its behavior. The platform combines AI observability, security, governance, orchestration and usage measurement.