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Synthesize Bio

Synthesize Bio develops generative genomics foundation models that predict human tissue and cell responses to drugs, diseases and experimental conditions. Its GEM models generate bulk and single-cell RNA-sequencing data from natural-language experiment descriptions, supporting virtual patient cohorts, biomarker research, safety analysis and clinical trial design. The company works with biotech and pharmaceutical teams to extend limited datasets and test development decisions before expensive studies. Its outputs support research and internal decision-making; the company states that they cannot currently serve as primary evidence in regulatory submissions.

Founded 2023

Team

Alice WalshChief Operating Officer
Ariel BrumbaughSenior Director of Business Development
Gregory KoytigerVice President of AI
Jeff LeekCo-Founder and Co-Chief Executive Officer
Liza RayChief of Staff and Vice President of Business Operations
Robert BradleyCo-Founder and Co-Chief Executive Officer
Stein SetvikVice President of Engineering

Investments

$10M2025-09-16Madrona Ventures