Startups

Synteny
Synteny develops MANIFOLD, an AI and experimental biology platform for designing protein therapeutics. It combines sequence, structure and physics models with large-scale laboratory measurements of molecular binding to predict affinity, specificity and unwanted interactions, then tests AI-designed molecules in high-throughput assays. Its first therapeutic application is T-cell receptor T-cell engagers for solid tumours and immunology. The UK-headquartered company also has a US presence; these are research and drug-development programmes rather than marketed or approved treatments.
