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Skin2Neuron

Sydney, New South Wales, Australia

Skin2Neuron develops regenerative cell therapies intended to replace neurons and rebuild synaptic connections lost in neurodegenerative disease. Its platform isolates, enriches and expands hair-follicle-derived neuroprecursor cells from a patient’s own skin; these naturally occurring cells can differentiate into neurons without genetic modification. Its lead program aims to deliver the cells into the hippocampus to treat Alzheimer’s disease. The company also develops customised neuronal cultures for research, disease modelling and drug testing, and explores applications in other neurological conditions. A University of Sydney spinout, Skin2Neuron has conducted rodent research and a veterinary trial in dogs with dementia. Its human therapy remains in development: a May2026 manufacturing agreement supports preparation for a planned first-in-human Phase1 trial in Australia, rather than an approved treatment. The legal company is Skin2Neuron Pty Ltd, also trading as S2N.

Founded 2019

Team

Adam DenleyExternal Patent Attorney — FPA (Principal at FPA)
Adam JohnsonHead of Laboratory and Co-inventor
Alvaro Pascual-LeoneAlvaro Pascual-LeoneScientific Advisory Committee Member
Alyona MylovanovaAdministrative Consultant
Angel JaramilloExecutive Team Member (founder-published 2025; exact rank/current tenure unverified)
Bill ManosDirector
Brad SheehanExecutive Team Member (founder-published 2025; exact rank/current tenure unverified)
Brendon BootChief Executive Officer
Dario GeraceSenior Scientific Officer
Dawn DriscollExecutive Team Member (founder-published 2025; exact rank/current tenure unverified)
Erica JacobsonScientific Advisory Committee Member
Helen WrayActing Chief Operating Officer and CMC Expert (company-published; current tenure unverified)
Henry BrodatyScientific Advisory Committee Member
Jeffrey SchweitzerScientific Advisory Committee Member
Kieran WilliamsExternal Patent Attorney — FPA (Principal at FPA)
Lars IttnerScientific Advisory Committee Member
Linah AlsaifBiomedical Engineer
Manon LevayerQuality Associate
Michael ValenzuelaFounder and Chief Scientific Officer · Former Chief Executive Officer (historical; end date unverified)
Rob McInnesExpert Consultant — IP Strategy and Commercial Deal Making
Robert DeansScientific Advisory Committee Member
Russell KnudsenScientific Advisory Committee Member
Sarah HennebryExternal Patent Attorney — FPA (Senior Associate at FPA)
Sarah HoustonSenior Product Development Officer
Thomas LönngrenThomas LönngrenAdvisory Board Member — Regulatory and Commercial Strategy
Tim OldhamExpert Consultant — Cell Manufacture and Biotech Commercialization

Investments

$—2024-10-21Artesian, SYNthesis BioVentures
$—Unknown datePsyMed Ventures