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RIME Therapeutics

Montreal, Canada

RIME Therapeutics is a Montreal biotechnology company developing an AI-assisted drug-discovery platform. Its function-first Disruptide platform uses AI-designed peptide probes to screen intracellular protein pockets in primary human cells. The approach links changes in disease-relevant cell biology to specific targets while generating binding and structure-activity data to guide subsequent drug chemistry. RIME combines human genetics, perturbation biology and machine learning to identify potential new therapeutic programs, initially including inflammation and immunology. Its published work is at the discovery-platform stage; it has not disclosed an approved medicine.

Founded 2025

Team

Dion MadsenBoard Member
Evelyn PauBoard Member
Jean-Christophe LachanceComputational Biology
Kelly-Anne PikeSVP Head of R&D
Laura DiGiovanniPlatform Innovation
Madison Bolger-MunroCorporate Strategy
Michael MeeCEO · Board Member
Norman DaveyScientific Co-Founder
Philip M. KimScientific Co-Founder
Riccardo CardilliHead of Finance
Vincent FrappierHead of Computational Biology

Investments

$—2026-04-30Amplitude Ventures