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NRG Therapeutics

NRG Therapeutics is a UK clinical-stage neuroscience company developing oral, brain-penetrant medicines for ALS and Parkinson’s disease. Its small molecules target the mitochondrial regulator NLRX1 to inhibit opening of the mitochondrial permeability transition pore, aiming to preserve neuronal energy production and reduce neuroinflammation and neuron loss. Lead candidate NRG5051 is being evaluated in a Phase 1 trial in healthy adults and people with ALS or Parkinson’s; Phase 2 proof-of-concept development in ALS is planned. The medicines are investigational.

Founded 2018

Team

Charlotte KremersCharlotte KremersInvestor Non-Executive Director
Claudio NessiClaudio NessiInvestor Non-Executive Director
Claus SundgreenChief Medical Officer
David BrocklebankDirector of Clinical Operations
David T. DexterInvestor Observer and Special Advisor on Parkinson’s
Florian MuellershausenInvestor Observer
Francesco DraettaFrancesco DraettaInvestor Non-Executive Director
Georgia FrostGeorgia FrostInvestor Non-Executive Director
Grant HawthorneCo-Founder and Chief Operating Officer
Hakan GokerHakan GokerInvestor Observer
Izzie FullerInvestor Observer
James SummersJames SummersScientific Advisory Board Chair
Jonathan SavidgeChair and Non-Executive Director
Kalpana MerchantScientific Advisory Board Member
Katherine JackmanKatherine JackmanInvestor Observer
Kathryn OliverDirector of Project Management
Laurence BarkerLaurence BarkerInvestor Observer
Mathias FrederiksenInvestor Non-Executive Director
Melanie LeitnerMelanie LeitnerScientific Advisory Board Member
Neil MillerCo-Founder, CEO and Executive Director
Pablo CironiInvestor Observer
Paul ThompsonChief Development Officer
Richard RutterCo-Founder and Chief Scientific Officer
Saoussen Ben HalimaSaoussen Ben HalimaInvestor Observer
Sarah AlmondVP of Translational Biology
Stevan DjuricStevan DjuricScientific Advisory Board Member

Investments