Marginum is a Finnish medical-device company developing fluorescence-based tissue detection technology for cancer surgery. Its HIVEN aspirate tissue detector measures fluorescent tissue flowing through the surgical suction tube and gives neurosurgeons near-real-time auditory feedback, integrating with existing operating-room workflows. Its current EU MDR-certified intended use is fluorescence-guided surgery for suspected high-grade gliomas using 5-aminolevulinic acid. The company combines optical hardware and its FLUOSIGHT software to help distinguish tumour tissue during resection; it is expanding European distribution and conducting U.S. clinical studies while pursuing FDA authorization.
