Firms

Mass General Brigham Ventures

Mass General Brigham Ventures

research.massgeneralbrigham.org

Mass General Brigham Ventures is the venture-investment business associated with the Mass General Brigham nonprofit academic healthcare system. Founded in 2008, it supports company creation and seed and early-stage life-sciences businesses, with follow-on investment through later development. Its focus includes therapeutics, medical devices, diagnostics and digital health, including precision neurology, mental health and clinical technology. The legal adviser is Mass General Brigham Ventures LLC, an exempt reporting adviser (CRD286361; SEC802-108906), formerly Partners Innovation Management Co. LLC and also using the Partners Innovation Fund name. These adviser aliases do not make each separately named legal fund the same entity. The current primary directory publishes eight investment-team members, three entrepreneurs in residence and eleven alumni entrepreneurs in residence. Alumni affiliations are historical; exact terms are unpublished. The March17,2026 ADV identifies Partners Innovation Fund LLC, Partners Innovation Fund II LP and Mass General Brigham Fund III LP. Regulatory gross asset values and manager assets under management are distinguished from actual fund closes. The healthcare system’s separate AI and Digital Innovation Fund and Amplify translational programs are not assumed to be external LP venture funds managed by this adviser. The manager’s current portfolio includes QurAlis, Nocion Therapeutics, InStride Health, Violet Therapeutics and other science-based companies; its historical portfolio includes neurodegeneration and hearing-loss companies. Portfolio evidence establishes institutional investment but does not disclose each cash ticket or financing date. The preserved historical organization identifier and all existing investment links remain associated with this same manager.

Founded
—
Type
Venture capital

Funds3

  • Partners Innovation Fund II LP$171M

    Partners Innovation Fund II LP exact SEC private-fund identifier 805-1451973283 in March17,2026 ADV. Regulatory gross asset value is not a closed fund size; unknown corpus and actual close dates remain NULL. Primary research-institute executive report confirms actual USD171million final close October31,2017.

  • Mass General Brigham Fund III LP—

    Mass General Brigham Fund III LP exact SEC private-fund identifier 805-1912266556 in March17,2026 ADV. Regulatory gross asset value is not a closed fund size; unknown corpus and actual close dates remain NULL.

  • Partners Innovation Fund LLC—

    Partners Innovation Fund LLC exact SEC private-fund identifier 805-9529159004 in March17,2026 ADV. Regulatory gross asset value is not a closed fund size; unknown corpus and actual close dates remain NULL.

Team

Operations and support

Adrian RayAdrian RayEntrepreneur in Residence
Barbara FoxBarbara FoxAlumni Entrepreneur in Residence (historical affiliation; exact dates unpublished)
Bhamini VaidialingamBhamini VaidialingamVenture Associate
Bill YelleBill YelleAlumni Entrepreneur in Residence (historical affiliation; exact dates unpublished)
Carl BerkeCarl BerkePartner
Cecilia FernándezCecilia FernándezEntrepreneur in Residence
Dave HavaDave HavaAlumni Entrepreneur in Residence (historical affiliation; exact dates unpublished)
David de GraafDavid de GraafAlumni Entrepreneur in Residence (historical affiliation; exact dates unpublished)
Ellen SheetsEllen SheetsAlumni Entrepreneur in Residence (historical affiliation; exact dates unpublished)
Jessica BallingerJessica BallingerAlumni Entrepreneur in Residence (historical affiliation; exact dates unpublished)
John RippleJohn RippleAlumni Entrepreneur in Residence (historical affiliation; exact dates unpublished)
Jonathan LevinsonJonathan LevinsonEntrepreneur in Residence
Julius KnowlesJulius KnowlesPartner
Meredith FisherMeredith FisherPartner
Niranjana NagarajanNiranjana NagarajanAlumni Entrepreneur in Residence (historical affiliation; exact dates unpublished)
Pauline Jen RyanPauline Jen RyanAlumni Entrepreneur in Residence (historical affiliation; exact dates unpublished)
Robert MillmanRobert MillmanAlumni Entrepreneur in Residence (historical affiliation; exact dates unpublished)
Roger KittermanRoger KittermanSenior Vice President, Venture, Business Development and Licensing and Managing Partner, Mass General Brigham Ventures
Sergine Brutus SweeneySergine Brutus SweeneyVenture Associate
Spiros JamasSpiros JamasAlumni Entrepreneur in Residence (historical affiliation; exact dates unpublished)
Stacey BrennerStacey BrennerSenior Director, Investor Relations and Finance
Thomas BackusThomas BackusVenture Associate

Co-investing

General Catalyst
.406 Ventures
Valtruis
FMZ Ventures
Sanofi Ventures

Investments

$30M2026-06-15InStrideGeneral Catalyst, .406 Ventures, Mass General Brigham Ventures, TPG Rise, FMZ Ventures, Valtruis
$30M2026-06-15InStride HealthGeneral Catalyst, .406 Ventures, Mass General Brigham Ventures, FMZ Ventures, Valtruis
$200M2025-02-12Abcuro, Inc.Bain Capital, New Enterprise Associates, Sanofi Ventures, Mass General Brigham Ventures, Pontifax, New Leaf Venture Partners
$30M2024InStrideGeneral Catalyst, .406 Ventures, Mass General Brigham Ventures, TPG Rise, Valtruis
$30M2024InStride HealthGeneral Catalyst, .406 Ventures, Mass General Brigham Ventures, Valtruis
$32M2022-09-28RipplARCH Venture Partners, General Catalyst, F-Prime Capital, GV, Mass General Brigham Ventures
$—Unknown dateQurAlisMass General Brigham Ventures
$30MUnknown dateInStride HealthGeneral Catalyst, .406 Ventures, Mass General Brigham Ventures, FMZ Ventures, Valtruis
$200MUnknown dateAbcuroBain Capital, Cormorant Asset Management, Sanofi Ventures, Mass General Brigham Ventures, Samsara BioCapital, Pontifax
$72MUnknown dateRomeARCH Venture Partners, Casdin Capital, Mirae Asset, Alexandria Venture Investments, Y Combinator, Sanofi Ventures, Mass General Brigham Ventures